Kızılgerdan Kuş Popülasyonu Biyoakustik Kayıtlarının Takibi İçin Kuş Sesi Tanıma Yöntemi Geliştirilmesi

Bu çalışmada, Kızılgerdan kuş popülasyonuna ait dört alt türün biyoakustik özelliklerinden tespiti için uygun öznitelik ve sınıflandırma yöntemi araştırılmıştır. Özniteliklerin belirlenmesi için Mel Frekansı Kepstrum Katsayıları temel alınmış ve bu katsayılardan istatistiksel parametreler yardımıyla hesaplanabilecek uygun öznitelik araştırması yapılmıştır. Sınıflandırma aşamasında Doğrusal Ayırma Ayıracı, Destek Vektör Makineleri ve k-En Yakın Komşuluk ve Ardışıl İleri Yönlü Öznitelik yöntemleri kullanılmıştır. Sınıflandırıcı parametreleri 10-kat çapraz doğrulama yöntemi ile eğitim setinde belirlenmiştir. Daha sonra, eğitilmiş sınıflandırıcı parametreleri test veri setine uygulanarak sınıflandırma doğruluğu elde edilmiştir. Sonuç olarak, çalışmamızda Mel Frekansı Kepstrum katsayıları temel alınarak hesaplanan ortalama, etkinlik ve karmaşıklık parametreleri k-En Yakın Komşuluk Yöntemi ile sınıflandırıldığında en iyi başarım elde edilmiştir. Önerdiğimiz yöntemin sınıflandırma başarımı eğitim kümesinde %97, test kümesinde ise %94 olarak elde edilmiştir

Evaluation of surgical-orthodontic treatments on impacted mandibular canines

Objective: The aim of the study was to evaluate patients treated for impacted mandibular canines through a combined surgical and orthodontic approach. Study Design: The cases which were made button operations of impacted mandibular canines were selected from 5100 panoramic radiographs taken from patients who made use of our oral and maxillofacial surgery services between January 1998 to April 2006. All of these selected patients were assessed radiographically. Pertinent information such as sex, age at the time of surgery, site of the unerupted tooth, space availability and any other associated pathoses were also recorded. These patients were called again, and the condition of the mandibular canines was evaluated with panoramic radiographs. If the tooth erupted in the right position and it was functional and asymptomatic, we assumed the treatment to be successful clinically. Results: In the present study, from 5100 patients, 69 patients had impacted mandibular canines and only 21 patients' teeth (a total of 23 teeth) were treated orthodontically. Sixteen impacted mandibular canine teeth of 14 patients erupted successfully. Two impacted canine were extracted, and only one canine tooth was transplanted to the normal position. Four patients ended the treatment because of failure of eruption. Conclusion: If a mandibular canine tooth is impacted, not only is surgical exposure sufficient but also traction force must be applied orthodontically after the surgical exposure. In addition, age influences the success of the treatment on impacted mandibular canine teeth more than the position and impaction level of the teeth. © Medicina Oral S. L

Serum levels of tumor necrosis factor-alpha, interleukin-6 and interleukin-8 are not increased in dyspeptic patients with Helicobacter pylori-associated gastritis.

INTRODUCTION: Helicobacter pylori (H. pylori) is a non-invasive microorganism causing intense gastric mucosal inflammatory and immune reaction. H. pylori-induced gastric mucosal cytokine overproduction has been clearly documented previously. The stomach has a large surface area and continuous spill-over of locally produced cytokines into the blood stream is a possibility. There are few and conflicting data on circulatory proinflammatory cytokine levels in patients with H. pylori infection. MATERIALS AND METHODS: Forty-two dyspeptic patients were enrolled into the study. The presence of H. pylori infection was diagnosed with antral histopathologic examination. After overnight fasting; serum samples were obtained from each patient to determine circulating interleukin (IL)-6, IL-8 and tumor necrosis factor-alpha (TNF-alpha) levels. RESULTS: H. pylori was shown in 30 cases using Giemsa stain in antral histopathologic evaluation. Twelve cases were negative for H. pylori staining. Both the age and sex distribution had an insignificant difference in both H pylori-positive and H. pylori-negative groups. The mean circulatory levels of IL-6, IL-8 and TNF-a in both groups were not different. The situation was same in respect to the serum levels of these cytokines and the degree of inflammation, H. pylori density and activation scores according to Sydney classification. CONCLUSION: We could not show elevated circulatory levels of IL-6, IL-8 and TNF-alpha in H. pylori-infected cases. We believe that H. pylori-related cytokine activation become concentrated on gastric mucosa and this pathogen-induced local inflammatory cascade does not cause changes in circulatory levels of these cytokines. Moreover, there is no correlation between the levels of serum cytokines and Sydney parameters

Kızılgerdan Kuş Popülasyonu Kayıtlarının Takibi İçin Kuş Sesi Tanıma Yöntemi Geliştirilmesi

Bu çalışmada, Kızılgerdan kuş popülasyonuna ait dört alt türün biyoakustik özelliklerinden tespiti için uygun öznitelik ve sınıflandırma yöntemi araştırılmıştır. Özniteliklerin belirlenmesi için Mel Frekansı Kepstrum Katsayıları temel alınmış ve bu katsayılardan istatistiksel parametreler yardımıyla hesaplanabilecek uygun öznitelik araştırması yapılmıştır. Sınıflandırma aşamasında Doğrusal Ayırma Ayıracı, Destek Vektör Makineleri ve k-En Yakın Komşuluk ve Ardışıl İleri Yönlü Öznitelik yöntemleri kullanılmıştır. Sınıflandırıcı parametreleri 10-kat çapraz doğrulama yöntemi ile eğitim setinde belirlenmiştir. Daha sonra, eğitilmiş sınıflandırıcı parametreleri test veri setine uygulanarak sınıflandırma doğruluğu elde edilmiştir. Sonuç olarak, çalışmamızda Mel Frekansı Kepstrum katsayıları temel alınarak hesaplanan ortalama, etkinlik ve karmaşıklık parametreleri k-En Yakın Komşuluk Yöntemi ile sınıflandırıldığında en iyi başarım elde edilmiştir. Önerdiğimiz yöntemin sınıflandırma başarımı eğitim kümesinde %97, test kümesinde ise %94 olarak elde edilmiştir

The significance of neutrophil-to-lymphocyte ratio in idiopathic epiretinal membrane

WOS: 000439166500005PubMed ID: 28608032To assess the levels of neutrophil-to-lymphocyte ratio (NLR) in patients with idiopathic epiretinal membrane (iERM) and to compare the NLR results of patients with iERM and healthy controls. This retrospective study enrolled 43 patients with iERM and 40 healthy subjects. Complete ophthalmologic examination and complete blood count measurements were performed of all subjects. Complete blood counts were performed within 2 h of blood collection. There was a significant difference in NLR between iERM and control groups (p <0.01). The receiver operating characteristics analysis revealed that the value of NLR to distinguish patients with iERM and controls was found to be 0.832. The best cutoff value was 1.90, with a sensitivity of 72% and specificity 70%. Our study for the first time provides evidence that subclinical systemic inflammation may cause or at least accompanies iERM using a novel biomarker NLR

Evaluation of surgical-orthodontic treatments on impacted mandibular canines

WOS: 000298087100012PubMed: 21196853Objective: The aim of the study was to evaluate patients treated for impacted mandibular canines through a combined surgical and orthodontic approach. Study Design: The cases which were made button operations of impacted mandibular canines were selected from 5100 panoramic radiographs taken from patients who made use of our oral and maxillofacial surgery services between January 1998 to April 2006. All of these selected patients were assessed radiographically. Pertinent information such as sex, age at the time of surgery, site of the unerupted tooth, space availability and any other associated pathoses were also recorded. These patients were called again, and the condition of the mandibular canines was evaluated with panoramic radiographs. If the tooth erupted in the right position and it was functional and asymptomatic, we assumed the treatment to be successful clinically. Results: In the present study, from 5100 patients, 69 patients had impacted mandibular canines and only 21 patients' teeth (a total of 23 teeth) were treated orthodontically. Sixteen impacted mandibular canine teeth of 14 patients erupted successfully. Two impacted canine were extracted, and only one canine tooth was transplanted to the normal position. Four patients ended the treatment because of failure of eruption. Conclusion: If a mandibular canine tooth is impacted, not only is surgical exposure sufficient but also traction force must be applied orthodontically after the surgical exposure. In addition, age influences the success of the treatment on impacted mandibular canine teeth more than the position and impaction level of the teeth

Tear osmolarity and tear film parameters in patients with ocular rosacea

WOS: 000387490000002PubMed ID: 26513720Objectives: The aim of this study was to evaluate tear osmolarity and tear film parameters in patients with ocular rosacea. Methods: In a single center, 25 eyes of 25 patients with ocular rosacea (group 1), 25 eyes of 25 patients with rosacea without ocular involvement (group 2), and 20 eyes of 20 healthy individuals (group 3) were evaluated using the Ocular Surface Disease Index (OSDI) questionnaire, Schirmer I test, tear film break-up time (TBUT), scoring of ocular surface fluorescein staining using modified Oxford scale, and tear osmolarity. Results: Tear osmolarity values, OSDI and Oxford scale scores were significantly higher in group 1 than in groups 2 and 3 (P < 0.001 for all). Schirmer I test and TBUT in group 1 were significantly lower than in groups 2 and 3 (P < 0.001 for all). There were no significant differences in OSDI, Schirmer I test, TBUT, Oxford scores, or tear osmolarity between groups 2 and 3 (P = 0.629, P = 0.175, P = 0.713, P = 865, and P = 0.388, respectively). Conclusions: This study showed that ocular rosacea is associated with tear hyperosmolarity and tear film dysfunction

In vivo generated autologous plasmin assisted vitrectomy in young patients

Background Autologous plasmin enzyme facilitates the induction of posterior vitreous detachment(PVD) during vitrectomy in young patients. We proposed the concept of in-vivo generated plasmin which is based on the injection of tissue plasminogen activator(t-PA) and autologous whole blood(AWB) into the vitreous cavity. The purpose of this pilot study is to report the efficacy of preoperative simultaneous intravitreal injection of(t-PA) and autologous whole blood in facilitating the intraoperative induction of PVD in young patients with various vitreoretinal pathologies. Methods Seventeen eyes of 16 young patients with various vitreoretinal pathologies requiring vitrectomy, who received simultaneous intravitreal injection of 0.1 ml of AWB and 25 mu g of t-PA, 3 days prior to surgery were retrospectively reviewed. Outcome measures were the number of attempts required to achieve successful intraoperative separation of the posterior hyaloid; the postoperative visual acuity; and intraoperative and postoperative complications. Results The mean age of the patients was 23.87 +/- 10.09 years, ranging from 10 to 39 years. Eight of 16 patients were men. The mean follow-up time was 19.35 +/- 5.04 months, ranging from 12 to 26 months. Surgical indications for vitrectomy were chronic retinal detachment (n = 7), traumatic retinal detachment without proliferative vitreoretinopathy(n = 3), traumatic macular hole(n = 1), secondary vasoproliferative tumor(n = 4) and optic pit maculopathy(n = 2). Patients with retinal detachment complicated with PVR and those who were older than 40 years of age were excluded from the study. Separation of the Weiss ring from the optic nerve head was achieved intraoperatively in all cases, with a mean number of 2.86 +/- 1.4 attempts. While the mean preoperative LogMAR visual acuity was 1.38 +/- 0.59, ranging from 2.40 to 0.50, it was a mean of 0.51 +/- 0.29, ranging from 1.00 to 0.10 at final postoperative exam(p < 0.001; paired samples t-test). No preoperative or intraoperative complications were noted. Conclusion Preoperative simultaneous intravitreal injection of 25 mu g t-PA with 0.1 ml of AWB facilitates the intraoperative induction of posterior vitreous detachment in young patients

The addition of dexamethasone to ondansetron for treatment of postoperative nausea and vomiting following day-case lumbar microdiscectomy

Amaç: Çalış mam ızda, deksametazonun ondansetronla kombinasyonunun lomber mikrodiskektomilerde postoperatif bulant ı kusmay ı (POBK) önlemedeki etkinliklerini karş ıla ş t ırmay ı amaçladık. Gereç ve Yöntem: Günübirlik mikrodiskektomi operasyonu uygulanacak American Society of Anesthesiologists (ASA) I-II, 60 hasta rastgele 3 gruba ayr ıldı: grup D; 8mg deksametazon, grup O; 4mg ondansetron, grup P; 8mg deksametazon ve 4mg ondansetron. Postoperatif bulantı ve kusma ve a ğ r ı s ıklığ ı ile antiemetik ve analjezik ihtiyaçlar ı cerrahi sonras ında 3-12 ve 24. saatlerde de ğ erlendirildi. Bulgular: Postoperatif ilk 3 saatte bulantı insidans ı grup D ve grup O’ya kıyasla grup P’de anlamlı olarak azalm ış t ı (p<0.046 ve p<0.021, s ıras ıyla). Bu dönemde ilave antiemetik kullanım ı, grup P’de grup D ve grup O’ya kıyasla anlamlı olarak azalm ış tı (p<0.030 ve p<0.023, s ıras ıyla). Çalış mam ızda; kadın cinsiyet, sigara içmeme, POBK veya ta ş ıt tutma hikâyesi POBK’nın tahmininde anlamlı risk faktörleriydi. Oral su/g ıda alma zamanı ve taburcu olma süreleri diğ er gruplara kıyasla grup P’de anlamlı olarak azalm ış ken (p<0.012, p<0.003 ve p<0.005, p<0.007, s ıras ıyla), POBK görülen hastalarda ise anlamlı olarak artm ış tı (p<0.007 ve p<0.029, s ıras ıyla). Sonuç: Günübirlik lomber mikrodiskektomilerde deksametazonun ondansetronla kombinasyonu antiemetik etkinliğ i arttırarak hastaların daha erken oral su/g ıda almalar ını ve daha erken taburcu olmalarını sa ğ lam ış tır.Objevtive: The aim of this study was to determine the effect of the combination of dexamethasone with ondansetron on postoperative nausea and vomiting (PONV) in patients undergoing lumbar microdiscectomy. Methods: ASA I–II, sixty patients undergoing day- case lumbar microdiscectomy were randomized into three groups: group D; (n=20) 8 mg dexamethasone, group O; (n=20) 4 mg ondansetron and group P; (n=20) 8 mg dexamethasone-4 mg ondansetron. The incidence of PONV and pain, the needs of antiemetics and analgesic were recorded 3-12 and 24th hours postoperatively. Results: The incidence of postoperative nausea in the first 3 hours was shorter in group P compared with group D and group O (p&lt;0.046 and p&lt;0.021, respectively). During this period, rescue antiemetic use was significantly decreased in group P compared with group D and group O (p&lt;0.030 and p&lt;0.023, respectively). Female gender, nonsmoking, history of motion sickness or PONV were risk factors for PONV. The oral water/nutrition intake and discharge time in group P was significantly decreased compared with the other groups (p&lt;0.012, p&lt;0.003 and p&lt;0.005, p&lt;0.007, respectively). It was significantly increased in patients who experienced PONV (p&lt;0.007 and p&lt;0.029, respectively). Conclusion: The combination of dexamethasone with ondasetron provided earlier oral water/nutrition intake and earlier discharge time by significantly increasing the antiemetic effectiveness